Running decreases knee intra-articular cytokine and cartilage oligomeric matrix concentrations: a pilot study
Fuente
Este artículo es originalmente publicado en:
https://www.ncbi.nlm.nih.gov/pubmed/27699484
http://link.springer.com/article/10.1007%2Fs00421-016-3474-z
De:
Hyldahl RD1, Evans A2, Kwon S2, Ridge ST2, Robinson E3, Hopkins JT2, Seeley MK2
Todos los derechos reservados para:
© 2017 Springer International Publishing AG. Part of Springer Nature.
Abstract
INTRODUCTION:
Regular exercise protects against degenerative joint disorders, yet the mechanisms that underlie these benefits are poorly understood. Chronic, low-grade inflammation is widely implicated in the onset and progression of degenerative joint disease.
PURPOSE:
To examine the effect of running on knee intra-articular and circulating markers of inflammation and cartilage turnover in healthy men and women.
CONCLUSIONS:
Running appears to decrease knee intra-articular pro-inflammatory cytokine concentration and facilitates the movement of COMP from the joint space to the serum.
KEYWORDS:
Biomarker; COMP; Exercise; GM-CSF; Ground reaction force; IL-15; IL-6; Inflammation; Knee joint; Osteoarthritis; Synovial fluid
Resumen
- PMID: 27699484 DOI: 10.1007/s00421-016-3474-z
- [PubMed – in process]
